Product ID:R9009, RIBONUCLEASE A FROM BOVINE (SUPDAT)
MSDS Date:01/01/1999
FSC:6505
NIIN:00N092677
Status Code:A
MSDS Number: CJVPQ

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

RIBONUCLEASE

CAS: 9001-99-4

RTECS: RF0760000

Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INHALATION,
INGESTION, OR SKIN ABSORPTION. MAY CAUSE EYE IRRITATION. MAY CAUSE
SKIN IRRITATION. MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND
UPPER RESPIRATORY TRACT. PRO LONGED OR REPEATED EXPOSURE MAY CAUSE
ALLERGIC REACTIONS IN CERTAIN SENSITIVE INDIVIDUALS. THE
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS
CONSCIOUS. CALL A PHYSICIAN. IN CASE OF SKIN CONTACT, FLUSH WITH
COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. REMOVE
CONTAMINATED CLOTHI NG AND SHOES. CALL A PHYSICIAN. IF INHALED,
REMOVE TO FRESH AIR. IF BREATHING BECOMES DIFFICULT, CALL A
PHYSICIAN. IN CASE OF CONTACT WITH EYES, FLUSH WITH COPIOUS AMOUNTS
OF WATER FOR AT LEAST 15 MIN UTES. ASSURE ADEQUATE FLUSHING BY
SEPARATING THE EYELIDS WITH FINGERS. CALL A PHYSICIAN.

Extinguishing Media:NONCOMBUSTIBLE. USE EXTINGUISHING MEDIA APPROPRIATE
TO SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND
EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR PROTECTIVE EQUIPMENT. SPILLED MATERIAL
SHOULD BE CAREFULLY WIPED UP OR MOISTENED WITH WATER AND REMOVED.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS
COMPLETE.

Handling and Storage Precautions:CAUTION: AVOID CONTACT AND INHALATION.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING. AVOID PROLONGED OR
REPEATED EXPOSURE.
Other Precautions:KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.

Respiratory Protection:NIOSH APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
MFR TRADE NAME/PART NO: PANCREAS MOLECULAR BIOLOGY REAGENT.

Solubility in Water:SOLUBLE
Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:NATURE OF DECOMPOSITION PRODUCTS NOT
KNOWN.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:RTECS #: RF0760000. NUCLEASE, RIBO-. TOXICITY
DATA: IPR-RAT LD50:392 MG/KG. 54IIAL -,56,1985. SCU-RAT LD50:290
MG/KG. 54IIAL 0,56,1985. IMS-RAT LD50:310 MG/KG. 54IIAL -,56,1985.
IPR-MUS LD50:250 MG/KG . 54IIAL -,,56,1985. IMS-MUS LD50:355 MG/KG.
54IIAL -,1985. ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL
SUBSTANCES (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN
RTECS FOR COMPLETE INFORM ATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:REVIEWS, STANDARDS, AND REGULATIONS.
OEL=MAK. EPA TSCA SECTION 8(B) CHEMICAL INVENTORY.